
Weeks 1-4
You're learning the routine and getting comfortable with your weekly protocol. Most participants focus on consistency and on noticing early changes in appetite and eating patterns.
Wolverine Recovery
Designed for people exploring support for mobility, recovery, connective tissue and healthy inflammatory signaling.
View programActive at-home study · 14 weeks
Unlike single-pathway approaches, retatrutide is being researched for how it interacts with several systems that influence metabolism: weight-loss pathways, energy balance, appetite-related signaling, and how the body uses nutrients. Every protocol starts with a short online assessment and is reviewed by a licensed clinician before anything is prescribed.
Complete at-home kit
Program cost
$1499
Full 14 weeks, kit and clinician support included. Payment plans available.
Your journey
Review what this study involves and whether it fits your goals.
Complete a short qualification form. About 2 minutes, 100% online.
Once approved, book a free call with a licensed clinician.
Everything arrives in one complete at-home kit, with all supplies included.
Ongoing participant support and educational guidance for the length of the program.
What makes this program different
Most people have tried diets, apps and willpower, and still feel stuck. This program takes a structured, clinician-supported approach instead.

Retatrutide is being researched for how it interacts with several systems that influence metabolism, appetite and energy balance, delivered here through a structured 14-week program.
Every protocol starts with a short online assessment and is reviewed by a licensed clinician. With a complete kit and step-by-step guidance, you always know what comes next.
How it works
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Your 14-week roadmap

You're learning the routine and getting comfortable with your weekly protocol. Most participants focus on consistency and on noticing early changes in appetite and eating patterns.

With the routine in place, attention shifts to trends over time: energy, meal patterns and how you feel across the week, not just day to day.

The final stretch is about the full picture and how things compare to where you started, so you and your clinician can talk through what comes next.
Quality you can check
Independent lab testing on program compounds.
Screened before anything ships to you.
Produced and packed domestically.
All purchases of Nuri programs are final. After your order is confirmed and medical intake filled out, we ship your entire 14 week program and are unable to reuse the peptides or kit after it has left our facility. Because of this, we are unfortunately unable to accept returns once it has been shipped.
Nuri’s Metabolic Health Program is a research program that uses Retatrutide experimentally under supervision. It is not an insurance-billed medical treatment, so we are not able to process insurance.We do, however, offer flexible payment options — including interest-free monthly plans for eligible applicants — to keep participation more accessible.
Follow-up appointments are essential to monitor progress, make adjustments if necessary, and address any concerns or questions. An intake form must be filled out before shipment, and we request final feedback on your results.Schedule a call at anytime during your program to discuss special needs. Be sure to consult with your own primary care provider before starting any new regimen.
Early studies suggest many people tolerate Retatrutide well. Most common are GI effects—nausea, indigestion/heartburn, stomach discomfort, diarrhea or constipation—especially during dose changes. Less common: headache, dizziness, fatigue, dry mouth, mild injection-site irritation, small heart-rate increases; seek urgent care for severe belly pain, repeated vomiting/diarrhea, signs of gallbladder issues or pancreatitis, allergic reaction, or low blood sugar (especially with glucose-lowering meds).The daily, natural supplements provided are specifically formulated to support the reduction and ease of these side effects.
Eligibility is determined based on your health history, current medications, and goals, along with safety criteria defined in protocol. To see if you may qualify, you’ll start with a short online pre-qualification form (about 5 minutes). If you pass that screen, you can schedule a call with a licensed clinician to decide whether participation is appropriate.
This 14-week program aims to support appetite control, earlier fullness, and steadier energy so it’s easier to stick to a nutrition and movement plan. Many clients report smaller portions, fewer cravings, and clothes fitting differently; the pace and magnitude vary. Your clinician monitors tolerance and can adjust dosing, nutrition, and habits to support healthy weight-management and blood-sugar responses.
Timing varies by person and dose. Many clients notice earlier fullness and fewer cravings within the first few weeks as dosing ramps, while others need more time and nutrition tweaks to feel a clear difference. If benefits feel minimal, discuss pacing and meal strategy with your clinician at your next check-in.
Within the Metabolic Health Program, Retatrutide is administered via subcutaneous injection as part of the investigational protocol.Detailed administration guidance, safety instructions, and support from licensed clinicians are provided to participants. We also encourage you to discuss any injection-based protocol with your own healthcare provider.
Retatrutide, and related compounds used in the Metabolic Health Program are experimental and not approved by the FDA to diagnose, treat, cure, or prevent any disease. This program is a research program, not standard medical care, and participation does not replace care from your personal physician or specialist.No specific results are promised or guaranteed.