A 14-week, at-home research protocol using Retatrutide under licensed clinical oversight and an FDA–HHS–approved IRB.
Built for adults looking to explore peptide-based tools for help with weight loss, and want to do so in a structured, supervised way instead of guessing alone.
Total Program Cost: $1,500
Flexible payment plans starting at $250/Month
Most people hear about BPC-157 and TB-500 through podcasts, social media, or online forums — and are then pushed toward anonymous “not for human use” websites with little context or oversight. Here is what makes joining a Nuri program unique:
1: Structured Protocol, Not Random Vials
2: Licensed Clinicians + FDA–HHS–Approved IRB
3: Vetted Sourcing and Testing
4: Radical Transparency Instead of Hype
This doesn’t remove all risk — the peptides used in our programs are still experimental — but it does mean you’re not navigating them alone or in the dark.
Our priority is safety, transparency, and honest expectations, not hype.
Retatrutide is a multi-receptor peptide that engages GLP-1, GIP, and glucagon pathways tied to appetite, glucose handling, and energy balance. By acting on these signals, it may help you feel full sooner, curb cravings, slow gastric emptying, and support healthy insulin and glucose responses — all of which can aid a structured weight-management plan alongside diet and activity. Clients report steadier energy and easier portion control; experiences vary.
Find your rhythm: consistent dosing, hydration, protein-forward meals, and daily movement. Many clients notice earlier fullness, smaller portions, and fewer between-meal cravings as satiety signaling kicks in. Mild digestive discomfort can happen; check in with your clinician for guidance and any dose adjustments.
Satiety tends to feel more predictable, making restaurant and social eating easier to navigate. You may notice steadier energy and better control of late-night snacking; some clients also report clothes fitting differently. Your clinician reviews tolerance and may fine-tune your plan.
Appetite patterns often feel “retrained,” and portion control becomes second nature. Focus shifts to sustaining habits—strength work, fiber, and sleep—to support ongoing weight-management efforts and healthy blood-sugar responses. You and your clinician review progress and decide whether to continue, taper, or move to maintenance.
*Payment plans available at checkout through Affirm, Klarna and Afterpay.
All of the compounds in our peptide studies are meticulously vetted for purity, efficacy, and safety. We use a neutral third party lab to test all of our products on a routine basis and offer published results - for quality you can trust.
All purchases of Nuri programs are final. After your order is confirmed and medical intake filled out, we ship your entire 14 week program and are unable to reuse the peptides or kit after it has left our facility. Because of this, we are unfortunately unable to accept returns once it has been shipped.
Nuri’s Metabolic Health Program is a research program that uses Retatrutide experimentally under supervision. It is not an insurance-billed medical treatment, so we are not able to process insurance.
We do, however, offer flexible payment options — including interest-free monthly plans for eligible applicants — to keep participation more accessible.
Follow-up appointments are essential to monitor progress, make adjustments if necessary, and address any concerns or questions. An intake form must be filled out before shipment, and we request final feedback on your results.
Schedule a call at anytime during your program to discuss special needs. Be sure to consult with your own primary care provider before starting any new regimen.
Early studies suggest many people tolerate Retatrutide well. Most common are GI effects—nausea, indigestion/heartburn, stomach discomfort, diarrhea or constipation—especially during dose changes.
Less common: headache, dizziness, fatigue, dry mouth, mild injection-site irritation, small heart-rate increases; seek urgent care for severe belly pain, repeated vomiting/diarrhea, signs of gallbladder issues or pancreatitis, allergic reaction, or low blood sugar (especially with glucose-lowering meds).
The daily, natural supplements provided are specifically formulated to support the reduction and ease of these side effects.
Eligibility is determined based on your health history, current medications, and goals, along with safety criteria defined in our IRB-approved protocol. To see if you may qualify, you’ll start with a short online pre-qualification form (about 5 minutes). If you pass that screen, you can schedule a call with a licensed clinician to decide whether participation is appropriate.
This 14-week program aims to support appetite control, earlier fullness, and steadier energy so it’s easier to stick to a nutrition and movement plan. Many clients report smaller portions, fewer cravings, and clothes fitting differently; the pace and magnitude vary. Your clinician monitors tolerance and can adjust dosing, nutrition, and habits to support healthy weight-management and blood-sugar responses.
Timing varies by person and dose. Many clients notice earlier fullness and fewer cravings within the first few weeks as dosing ramps, while others need more time and nutrition tweaks to feel a clear difference.
If benefits feel minimal, discuss pacing and meal strategy with your clinician at your next check-in.
Within the Metabolic Health Program, Retatrutide is administered via subcutaneous injection as part of the investigational protocol.
Detailed administration guidance, safety instructions, and support from licensed clinicians are provided to participants. We also encourage you to discuss any injection-based protocol with your own healthcare provider.
Retatrutide, and related compounds used in the Metabolic Health Program are experimental and not approved by the FDA to diagnose, treat, cure, or prevent any disease. This program is a research program, not standard medical care, and participation does not replace care from your personal physician or specialist.
No specific results are promised or guaranteed.
265 US-70, 85543
Pima, AZ
*Our programs and supplements are not intended to diagnose, treat, cure, or prevent any disease